Senior Software Engineer

Silicon Valley, CA, United States • $120k - $160k • 0.1% - 0.5%


Role Location

  • Silicon Valley, CA, United States


  • $120k - $160k
  • 0.1% - 0.5%


101 - 250 people


1455 Adams Dr
Menlo Park, CA, 94025, US

Tech Stack

  • Python
  • Django
  • Heroku
  • AWS
  • Clojure
  • PostgreSQL

Role Description

BillionToOne (Y Combinator S17) is hiring a Senior Software Engineer in a leadership role. This is an extremely impactful and cross-departmental position that will make a real difference in people's lives from day 1. You will be a leader in engineering in a very fast-growth environment (we grew from ~10 to ~50 employees in the past year) with the opportunity to grow and lead an engineering team in ~2 years. No biotech experience is necessary, but a growth and collaboration mindset & end-to-end ownership is key.

We apply bioengineering and machine learning principles to diagnostics in order to build truly quantitative molecular tests. Our QCT platform improves the resolution of cell-free DNA testing by >1000x fold and enables novel tests for both prenatal and oncology care. You will collaborate with cross-functional teams to build backend infrastructure, laboratory automation tools, and tools to communicate genetic results to doctors and patients.


  • 2-5 years as a full-stack engineer touching frontend, database, backend
  • Very strong Python expertise
  • Deep knowledge of web technologies: REST, relational databases, HTTP, javascript
  • Experience with a web framework in Python, e.g. Django or Flask
  • Strong desire to make an impact both through many small tools and large product development in a fast-paced environment

About BillionToOne

We've developed a DNA molecular counter with 1000x better precision. Our DNA technology underpins the first and only non-invasive prenatal test for cystic fibrosis, sickle cell disease, and other severe inherited disorders.

Company Culture

  1. Profoundly Impactful. We hire superstars for every position that are internally motivated and passionate to be excellent. We empower everyone to make high-impact decisions, use high-leverage tools, and solve big problems.

  2. Collaborative and kind. We are a highly disciplinary team comprised of engineers, PhD scientists, lab scientists, product, marketing, and commercial. Everyone participates in discussions and learns from each other.

  3. Innovative and Creative. We invent new solutions, make the old new, do the opposite.

  4. Patient-focused. Every decision is viewed through the lens, What is best for the patient?

Interested in this role?
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