Cofactor Genomics

San Francisco
11 - 25 Employees
< 10 Engineers
$25M - $50M Funding
Pre-Series A

Cofactor Genomics uses RNA to help researchers and clinicians understand, diagnose, and predict drug response for the 95% of disease that can’t be assessed by DNA alone.

Founded by three former Human Genome Project scientists, Cofactor has built a proprietary platform capable of overcoming the chemical and computational challenges of performing complex RNA fingerprint analysis on clinical-grade human samples. Cofactor has contracts to provide RNA sequencing and analysis services to the research arms of eight of the world’s largest pharma and biotech companies, and is in the process of commercializing a suite of clinical diagnostic assays targeting oncologic, immunologic, and neurodegenerative diseases.

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Why join us?
  • Cofactor’s RNA-based technologies are aimed at advancing cancer care through molecular profiling and software-driven diagnostics.

    Current statistics from the US, Canada, and the UK estimate as much as 50% of the current population will be diagnosed with cancer, with 25% ultimately succumbing to the disease. Those are sobering statistics that Cofactor aims to change.

  • We've raised over $20 million, including $18 million in an oversubscribed Series A round in September 2017. We're backed by a world-class group of investors, including Menlo Ventures, Y Combinator, Stanford University, Data Collective (DCVC), and Ascension Ventures — which represents 13 hospital networks with over 500 hospitals across 42 states ($90 billion in annual revenue).

    Founded by three former Human Genome Project scientists, we've got a fantastic team, and we're looking for the best to join us on our mission and help build the future of diagnostics.

  • With its combination of cutting-edge molecular technology and machine learning-driven interpretation software, Cofactor is uniquely positioned to bring RNA-based disease insights into the clinic, expanding the reach of precision medicine to a broader class of molecularly targeted drugs whose efficacy can’t be assessed with DNA alone.


Engineering at Cofactor Genomics
Engineering team and processes

Engineers at Cofactor take ownership over their area of responsibility, working directly with stakeholders to develop the spec, timeline, and scope. We encourage best practices for developing robust code, and look forward to you bringing what you know as well.

Most importantly, our engineers learn new skills and techniques from each other and jointly create a great engineering culture together.

Technical Challenges

We are growing rapidly, and need to beef up our architecture to achieve: (1) the rapid yet stable introduction of new code and features into production, (2) automatic scaling of higher throughput on the backend, and (3) a robust customer-facing web application experience.

We're looking to you to deploy all of your skills and experience to build a powerful, performant big data infrastructure.

Projects you might work on
  • Develop and deploy a system for efficiently queuing and processing arbitrary numbers of datasets in the 100-GB range.

  • Design and implement automated testing approaches for a web application, including functional, performance, and security considerations.

  • Build a customer-facing interactive data visualization tool to enable easy interpretation of thousands of data points.

Tech stack
RNA
Python
Pandas
AWS

Working at Cofactor Genomics

We value people who are supportive and generous in a collaborative engineering culture. Communication is always key, and we encourage everyone at Cofactor to err on the side of over-communicating, while also proactively seeking out information as needed.

If you take pride in building products that are valuable to users, enjoy continually learning and improving, are highly self-motivated, and crave ownership and impact... you'll fit right in.

Free Food

Plenty of good coffee, drinks and snacks

Beautiful Office

Beautiful, light-filled office in China Basin, just across from AT&T Park

Health Insurance

Medical, dental, and vision insurance, and HSA available

Flexible Hours

We know that we all have stuff to attend to. If you will be out of the office for a brief period like 1-2 hours for a personal matter, no need to take formal time off — just let folks know.

401(k) Contribution

401k program with automatic 3% contribution from Cofactor


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