Freenome

sf, silicon_valley
51 - 100 Employees
11 - 25 Engineers
$100M+ Funding
Series B

At Freenome, we’re building a multi-omics platform that ingests clinical-grade, high-dimensional, biological data for early cancer detection. We are guiding the bleeding edge of scientific research; no technology has ever been created to support this level of innovation.

We’re a diverse group of Engineers building tools and services which enable our Computational, Molecular, and ML Scientists to turn great research into even better products. We will create actionable insights for health systems and will guide change for the way doctors think about early detection of colon cancer. As our technology scales, we will incorporate the detection of other diseases into Freenome’s product.

Freenome photo 1 Freenome photo 2
Active Roles
Why join us?
  • We closed a $165M Series B on July 24, the second-largest ever in the diagnostic space. Total funds raised equal $243M from the most well-respected venture firms across tech and life sciences, including RA Capital, Polaris Partners, Perceptive Advisors, Andreessen Horowitz, funds and accounts advised by T. Rowe Price Associates, Inc., GV (formerly Google Ventures), Roche Venture Fund, Kaiser Permanente Ventures, American Cancer Society’s BrightEdge Ventures, Data Collective Venture Capital, and Verily Life Sciences (formerly Google Life Sciences). These funds will allow us to launch our FDA validation study in Q1 2020 for our colorectal cancer screen and rapidly scale the Freenome team.

  • Freenome recently published our first peer-reviewed paper in BMC Cancer showing our pioneering ability to predict the detection of colon cancer in retrospective samples at 85% sensitivity / 85% specificity in cell-free DNA (cfDNA). Blood-based methods using cfDNA are the latest advancement under development to use as an alternative to existing screening tests which are not sufficient to detect cancer at its earliest stage.

    Do you want to be a trailblazer? This is the place.

    https://bmccancer.biomedcentral.com/articles/10.1186/s12885-019-6003-8 https://www.freenome.com/blog-freenome/2018/10/16/a-deeper-dive-into-data-from-our-colorectal-cancer-screening-program?p

  • Our scientific approach using multiomics highlights our longterm vision: building a platform to ingest clinical-grade, high-dimensional biological data which will allow us to build a sustainable, scalable pipeline of products, from a blood test to detect colon cancer, to multicancer screening, and beyond.


Engineering at Freenome
Engineering team and processes

The engineering team is organized into Scrum and Kanban teams running in 2-week sprints. We use agile SDLC and DevOps strategies. Engineers are key stakeholders in our matrixed organization, interacting with Molecular, Computational, and ML Scientists day in and day out.

Technical Challenges

We’re bringing together industry advancements in science and technology to build the systems and software which enable our teams to spot the patterns in noisy biological signals via blood plasma.

We are building a state-of-the-art, workflow-based systems supporting our bioinformatics pipeline and ML platform to be the envy of the biotech field, as well as improve and save peoples’ lives. This will be the world's largest discoverable colorectal cancer dataset, properly processed and with longitudinal data over time which allows us to apply machine learning on a scale never before possible. Think ImageNet, but for colorectal cancer and eventually beyond.

Our software and systems must be highly adaptable for the various scientific users of our company. This means you will work cross-functionally with other teams throughout the organization, driving your own initiatives and building human-centric systems from the ground up.

Projects you might work on
  • Our machine learning platform is how Freenome creates novel, groundbreaking, and product-creating classifiers. It must be flexible enough to handle rapid experimentation while also meeting strict regulatory goals for FDA approved Software as a Medical Device guideline. Careful considerations must be made for today’s needs and development while considering scaling for the future once our product is on the market. Some challenges include - Data validity/synchronization in a microservice-land - Realtime single-source-of-truth data vs. snapshot learning models - How to realistically handle petabyte-scale data

  • Research Software and Data Pipelines: Going from raw data to usable, quality-controlled data in a trackable, stable, reliable, replicable manner. Our teams sequence an individual’s full genome, which equates to about 1TB of data per person, to analyze and decode the billions of complex patterns associated with the body's response to specific tumor types.

    (https://bmccancer.biomedcentral.com/articles/10.1186/s12885-019-6003-8, https://www.freenome.com/blog-freenome/2018/10/16/a-deeper-dive-into-data-from-our-colorectal-cancer-screening-program?p)

  • Long term projects and bigger picture growth include continuing to integrate with external components to commercialize the product, such as CRM, billing, etc. We’re laying the groundwork and your role will directly impact the future roadmap and vision as the team continues to scale.

Tech stack
Google Cloud
JavaScript
Python
Docker
Kubernetes
NGINX

Working at Freenome

Freenomers are technical and creative, visionary and grounded, empathetic and passionate. We build teams around divergent expertise, which allows us to solve problems and uncover opportunities in unique ways. Freenomers are some of the most talented experts in their fields, coming together to advance healthcare one breakthrough at a time.

We value empathy, integrity, and trust in one another. That means embracing other’s perspectives, those of our coworkers and those of the patients and communities we serve. It means knowing when to push, and when to listen. At Freenome, we give each other the benefit of the doubt in the belief that we’re all working as a team toward the same goals, and empower others to grow in a collaborative environment.

Free Food
Gym/Fitness
Beautiful Office
Company Retreats
Workshops/Conferences
Maternal/Paternal Leave

Also a great onsite daycare facility for kiddos 2+!

Flexible Hours
Health Insurance
Team Activities
Work from Home

Our Engineers can WFH one day/week if they like.

Transportation
Other

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